Difference between revisions of "MediaWiki:Gadget-calculator-neuro.js"
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Chris Rishel (talk | contribs) (Created page with "( function() { mw.calculators.addUnitsBases( { temperature: { toString: function( units ) { units = units.replace( 'deg', '°' ); return units; } } } ); mw.calculators.addVariables( { paCO2: { name: 'PaCO<sub>2</sub>', type: 'number', abbreviation: 'PaCO<sub>2</sub>', minValue: '20 mmHg', defaultValue: '40 mmHg',...") |
Chris Rishel (talk | contribs) |
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'Tameem A, Krovvidi H, Cerebral physiology, Continuing Education in Anaesthesia Critical Care & Pain, Volume 13, Issue 4, August 2013, Pages 113–118, https://doi.org/10.1093/bjaceaccp/mkt001' | 'Tameem A, Krovvidi H, Cerebral physiology, Continuing Education in Anaesthesia Critical Care & Pain, Volume 13, Issue 4, August 2013, Pages 113–118, https://doi.org/10.1093/bjaceaccp/mkt001' | ||
], | ], | ||
searchData: 'cmro2', | |||
calculate: function( data ) { | calculate: function( data ) { | ||
// Temperature is included as an optional variable to generate the input. | // Temperature is included as an optional variable to generate the input. | ||
Revision as of 15:49, 5 April 2022
( function() {
mw.calculators.addUnitsBases( {
temperature: {
toString: function( units ) {
units = units.replace( 'deg', '°' );
return units;
}
}
} );
mw.calculators.addVariables( {
paCO2: {
name: 'PaCO<sub>2</sub>',
type: 'number',
abbreviation: 'PaCO<sub>2</sub>',
minValue: '20 mmHg',
defaultValue: '40 mmHg',
maxLength: 3,
units: [
'mmHg'
]
},
temperature: {
name: 'Temperature',
type: 'number',
abbreviation: 'Temp',
minValue: '20 degC',
maxValue: '44 degC',
defaultValue: '37 degC',
maxLength: 5,
units: [
'degC',
'degF'
]
}
} );
// Neuro
mw.calculators.addCalculations( {
brainMass: {
name: 'Brain mass',
data: {
variables: {
optional: [ 'age', 'gender' ]
}
},
digits: 0,
units: 'gwt',
description: 'This calculation will give a more precise estimate of brain mass if age and/or gender are provided.',
references: [
'Dekaban AS. Changes in brain weights during the span of human life: relation of brain weights to body heights and body weights. Ann Neurol. 1978 Oct;4(4):345-56. doi: 10.1002/ana.410040410. PMID: 727739.'
],
calculate: function( data ) {
var age = data.age ? data.age.toNumber( 'yr' ) : null;
var gender = data.gender ? data.gender : null;
var brainMassFemale = 1290;
var brainMassMale = 1450;
if( age !== null ) {
if( age <= 10 / 365 ) {
// <=10 days
brainMassFemale = 360;
brainMassMale = 380;
} else if( age <= 4 * 30 / 365 ) {
// Less than 4 months. This is a gap in the reported data of the paper, so linearly interpolate?
var ageFactor = 1 - ( 4 * 30 / 365 - age ) / ( 4 * 30 / 365 - 10 / 365 );
brainMassFemale = 360 + ageFactor * ( 580 - 360 );
brainMassMale = 380 + ageFactor * ( 640 - 380 );
} else if( age <= 8 * 30 / 365 ) {
// <=8 months
brainMassFemale = 580;
brainMassMale = 640;
} else if( age <= 18 * 30 / 365 ) {
// <=18 months
brainMassFemale = 940;
brainMassMale = 970;
} else if( age <= 30 * 30 / 365 ) {
// <=30 months
brainMassFemale = 1040;
brainMassMale = 1120;
} else if( age <= 43 * 30 / 365 ) {
// <=43 months
brainMassFemale = 1090;
brainMassMale = 1270;
} else if( age <= 5 ) {
brainMassFemale = 1150;
brainMassMale = 1300;
} else if( age <= 7 ) {
brainMassFemale = 1210;
brainMassMale = 1330;
} else if( age <= 9 ) {
brainMassFemale = 1180;
brainMassMale = 1370;
} else if( age <= 12 ) {
brainMassFemale = 1260;
brainMassMale = 1440;
} else if( age <= 15 ) {
brainMassFemale = 1280;
brainMassMale = 1410;
} else if( age <= 18 ) {
brainMassFemale = 1340;
brainMassMale = 1440;
} else if( age <= 21 ) {
brainMassFemale = 1310;
brainMassMale = 1450;
} else if( age <= 30 ) {
brainMassFemale = 1300;
brainMassMale = 1440;
} else if( age <= 40 ) {
brainMassFemale = 1290;
brainMassMale = 1440;
} else if( age <= 50 ) {
brainMassFemale = 1290;
brainMassMale = 1430;
} else if( age <= 55 ) {
brainMassFemale = 1280;
brainMassMale = 1410;
} else if( age <= 60 ) {
brainMassFemale = 1250;
brainMassMale = 1370;
} else if( age <= 65 ) {
brainMassFemale = 1240;
brainMassMale = 1370;
} else if( age <= 70 ) {
brainMassFemale = 1240;
brainMassMale = 1360;
} else if( age <= 75 ) {
brainMassFemale = 1230;
brainMassMale = 1350;
} else if( age <= 80 ) {
brainMassFemale = 1190;
brainMassMale = 1330;
} else if( age <= 85 ) {
brainMassFemale = 1170;
brainMassMale = 1310;
} else {
brainMassFemale = 1140;
brainMassMale = 1290;
}
}
if( gender === 'F' ) {
return brainMassFemale;
} else if( gender === 'M' ) {
return brainMassMale;
} else {
return ( brainMassFemale + brainMassMale ) / 2;
}
}
},
cerebralBloodVolume: {
name: 'Cerebral blood volume',
abbreviation: 'CBV',
data: {
calculations: {
required: [ 'brainMass' ]
}
},
units: 'mL',
description: '4 mL per 100g of brain mass',
references: [
'Tameem A, Krovvidi H, Cerebral physiology, Continuing Education in Anaesthesia Critical Care & Pain, Volume 13, Issue 4, August 2013, Pages 113–118, https://doi.org/10.1093/bjaceaccp/mkt001'
],
calculate: function( data ) {
var brainMass = data.brainMass.toNumber( 'gwt' );
return 4 * brainMass / 100;
}
},
cerebralMetabolicRateFactor: {
name: 'Cerebral metabolic rate factor',
abbreviation: '%CMR',
data: {
variables: {
optional: [ 'temperature' ]
}
},
description: '7% change in CMR for every 1 °C change in temperature',
references: [
'Tameem A, Krovvidi H, Cerebral physiology, Continuing Education in Anaesthesia Critical Care & Pain, Volume 13, Issue 4, August 2013, Pages 113–118, https://doi.org/10.1093/bjaceaccp/mkt001'
],
calculate: function( data ) {
var temperature = data.temperature ? data.temperature.toNumber( 'degC' ) : null;
var cerebralMetabolicRateFactor = 1;
if( temperature ) {
cerebralMetabolicRateFactor += 0.07 * ( temperature - 37 );
}
return cerebralMetabolicRateFactor;
}
},
cerebralMetabolicRateO2: {
name: 'Cerebral metabolic rate (O<sub>2</sub>)',
abbreviation: 'CMRO<sub>2</sub>',
data: {
calculations: {
required: [ 'brainMass', 'cerebralMetabolicRateFactor' ]
},
variables: {
optional: [ 'temperature' ]
}
},
units: 'mL/min',
description: '<ul><li>3 mL O<sub>2</sub>/min per 100g of brain mass</li><li>If temperature is provided, adjusts estimate using 7% change in CMR for every 1 °C change in temperature</li></ul>',
references: [
'Tameem A, Krovvidi H, Cerebral physiology, Continuing Education in Anaesthesia Critical Care & Pain, Volume 13, Issue 4, August 2013, Pages 113–118, https://doi.org/10.1093/bjaceaccp/mkt001'
],
searchData: 'cmro2',
calculate: function( data ) {
// Temperature is included as an optional variable to generate the input.
// It is used by cerebralMetabolicRateFactor, which is an internal calculation not typically shown.
var brainMass = data.brainMass.toNumber( 'gwt' );
var cerebralMetabolicRateFactor = data.cerebralMetabolicRateFactor.toNumber();
return cerebralMetabolicRateFactor * 3 * brainMass / 100;
}
},
cerebralMetabolicRateGlucose: {
name: 'Cerebral metabolic rate (Glucose)',
abbreviation: 'CMR<sub>glu</sub>',
data: {
calculations: {
required: [ 'brainMass', 'cerebralMetabolicRateFactor' ]
}
},
units: 'mg/min',
description: '<ul><li>5 mg glucose/min per 100g of brain mass</li><li>7% change in CMR for every 1 °C change in temperature</li></ul>',
references: [
'Tameem A, Krovvidi H, Cerebral physiology, Continuing Education in Anaesthesia Critical Care & Pain, Volume 13, Issue 4, August 2013, Pages 113–118, https://doi.org/10.1093/bjaceaccp/mkt001'
],
calculate: function( data ) {
var brainMass = data.brainMass.toNumber( 'gwt' );
var cerebralMetabolicRateFactor = data.cerebralMetabolicRateFactor.toNumber();
return cerebralMetabolicRateFactor * 5 * brainMass / 100;
}
},
cerebralBloodFlow: {
name: 'Cerebral blood flow',
abbreviation: 'CBF',
data: {
calculations: {
required: [ 'brainMass', 'cerebralMetabolicRateFactor' ]
},
variables: {
optional: [ 'paCO2' ]
}
},
units: 'mL/min',
description: '<ul><li>50 mL/min per 100g of brain mass.</li><li>Every mmHg in PaCO2 changes CBF by 1.5 mL/min per 100g of brain mass.</li><li>Cerebral blood flow and cerebral metabolic rate are coupled. Factors that alter CMR (e.g. temperature) will proportionally alter CBF.</li>',
references: [
'Tameem A, Krovvidi H, Cerebral physiology, Continuing Education in Anaesthesia Critical Care & Pain, Volume 13, Issue 4, August 2013, Pages 113–118, https://doi.org/10.1093/bjaceaccp/mkt001',
'Brian JE Jr. Carbon dioxide and the cerebral circulation. Anesthesiology. 1998 May;88(5):1365-86. doi: 10.1097/00000542-199805000-00029. PMID: 9605698.'
],
calculate: function( data ) {
var brainMass = data.brainMass.toNumber( 'gwt' );
var cerebralMetabolicRateFactor = data.cerebralMetabolicRateFactor.toNumber();
var paCO2 = data.paCO2.toNumber( 'mmHg' );
var cerebralBloodFlow = cerebralMetabolicRateFactor * 50 * brainMass / 100;
if( paCO2 ) {
// CO2 reductions don't reduce CBF more than 50%
var minCerebralBloodFlow = cerebralBloodFlow / 2;
cerebralBloodFlow += 1.5 * brainMass / 100 * ( paCO2 - 40 );
cerebralBloodFlow = math.max( cerebralBloodFlow, minCerebralBloodFlow );
}
return cerebralBloodFlow;
}
}
} );
}() );