Difference between revisions of "MediaWiki:Gadget-calculator-drugDosage.js"

Revision as of 16:56, 30 August 2021

/**
 * @author Chris Rishel
 */
( function() {
    /**
     * DrugColor data
     */
    mw.calculators.addDrugColors( {
        anticholinergic: {
            primaryColor: '#9fc96b'
        },
        benzodiazepine: {
            primaryColor: '#f57921'
        },
        benzodiazepineReversal: {
            parentColor: 'benzodiazepine',
            striped: true
        },
        cardiovascularAgonist: {
            primaryColor: '#e1c9df'
        },
        cardiovascularAntagonist: {
            parentColor: 'cardiovascularAgonist',
            striped: true
        },
        default: {
            primaryColor: '#fff',
            highlightColor: '#fff'
        },
        desflurane: {
            primaryColor: '#0072ae'
        },
        enflurane: {
            primaryColor: '#f9a23b'
        },
        epinephrine: {
            parentColor: 'cardiovascularAgonist',
            highlightColor: '#000'
        },
        halothane: {
            primaryColor: '#b20107'
        },
        isoflurane: {
            primaryColor: '#92278f'
        },
        localAnesthetic: {
            primaryColor: '#b6b2a9'
        },
        neuromuscularBlocker: {
            primaryColor: '#f15563'
        },
        neuromuscularBlockerReversal: {
            parentColor: 'neuromuscularBlocker',
            striped: true
        },
        nitrousOxide: {
            primaryColor: '#004f7c'
        },
        opioid: {
            primaryColor: '#6bc8ea'
        },
        opioidReversal: {
            parentColor: 'opioid',
            striped: true
        },
        sedativeHypnotic: {
            primaryColor: '#f7e20a'
        },
        sevoflurane: {
            primaryColor: '#ffe715'
        },
        succinylcholine: {
            parentColor: 'neuromuscularBlocker',
            highlightColor: '#000'
        }
    } );



    /**
     * DrugPopulation data
     */
    mw.calculators.addDrugPopulations( {
        general: {
            name: 'General',
        },
        general120kg: {
            name: 'General (&GreaterEqual;120kg)',
            abbreviation: '&GreaterEqual;120kg',
            variables: {
                weight: {
                    min: '120 kgwt'
                }
            }
        },
        neonatal: {
            name: 'Neonatal',
            variables: {
                age: {
                    max: '0 yo'
                }
            }
        },
        pediatric: {
            name: 'Pediatric',
            variables: {
                age: {
                    min: '0 yo',
                    max: '17.9 yo'
                }
            }
        },
        geriatric: {
            name: 'Geriatric',
            variables: {
                age: {
                    min: '65 yo'
                }
            }
        }
    } );



    /**
     * DrugRoute data
     */
    mw.calculators.addDrugRoutes( {
        iv: {
            name: 'Intravenous',
            abbreviation: 'IV',
            default: true
        },
        im: {
            name: 'Intramuscular',
            abbreviation: 'IM'
        },
        po: {
            name: 'Oral',
            abbreviation: 'PO'
        },
        pr: {
            name: 'Rectal',
            abbreviation: 'PR'
        }
    } );



    /**
     * DrugIndication data
     */
    mw.calculators.addDrugIndications( {
        abxProphylaxis: {
            name: 'Antimicrobial prophylaxis',
            abbreviation: 'Abx.'
        },
        acls: {
            name: 'ACLS',
            abbreviation: 'ACLS'
        },
        analgesia: {
            name: 'Analgesia',
            abbreviation: 'Analgesia'
        },
        anaphylaxis: {
            name: 'Anaphylaxis',
            abbreviation: 'Anaphylaxis'
        },
        anxiolysis: {
            name: 'Anxiolysis',
            abbreviation: 'Anxiety'
        },
        bradycardia: {
            name: 'Bradycardia',
            abbreviation: 'Bradycardia'
        },
        generalAnesthesia: {
            name: 'General anesthesia',
            abbreviation: 'GA'
        },
        hypotension: {
            name: 'Hypotension',
            abbreviation: 'Hypoten.'
        },
        hypocalcemia: {
            name: 'Hypocalcemia',
            abbreviation: 'Hypo Ca<sup>2+</sup>'
        },
        intubation: {
            name: 'Intubation',
            abbreviation: 'Intubation'
        },
        malignantHyperthermia: {
            name: 'Malignant hyperthermia',
            abbreviation: 'MH'
        },
        neuromuscularBlockade: {
            name: 'Neuromuscular blockade',
            abbreviation: 'NMB'
        },
        neuromuscularBlockadeReversal: {
            name: 'Neuromuscular blockade reversal',
            abbreviation: 'NMB reversal'
        },
        mac: {
            name: 'Monitored anesthesia care',
            abbreviation: 'MAC'
        },
        ponv: {
            name: 'Postoperative nausea & vomiting',
            abbreviation: 'PONV'
        },
        tiva: {
            name: 'Total intravenous anesthesia',
            abbreviation: 'TIVA'
        }
    } );



    /**
     * Drug data
     */



    /**
     * Acetaminophen
     */
    mw.calculators.addDrugs( {
        acetaminophen: {
            name: 'Acetaminophen',
            dosages: [
                {
                    indication: 'analgesia',
                    population: 'general',
                    dose: {
                        dose: '1 g'
                    },
                    description: 'Max dose 4 g/day. Use caution in hepatic impairment.'
                }, {
                    indication: 'analgesia',
                    population: 'general',
                    route: 'po',
                    dose: {
                        min: '650 mg',
                        max: '1 g'
                    },
                    description: 'Max dose 4 g/day. Use caution in hepatic impairment.'
                }, {
                    indication: 'analgesia',
                    population: 'general',
                    route: 'pr',
                    dose: {
                        min: '650 mg',
                        max: '1 g'
                    },
                    description: 'Max dose 4 g/day. Use caution in hepatic impairment.'
                }, {
                    indication: 'analgesia',
                    population: 'pediatric',
                    dose: {
                        dose: '15 mg/kg',
                        absoluteMax: '1 g'
                    },
                    description: 'Max 75 mg/kg/day or 4 g/day (whichever is less). Use caution in hepatic impairment.'
                }, {
                    indication: 'analgesia',
                    population: 'pediatric',
                    route: 'po',
                    dose: {
                        dose: '15 mg/kg',
                        absoluteMax: '1 g'
                    },
                    description: 'Max 75 mg/kg/day or 4 g/day (whichever is less). Use caution in hepatic impairment.'
                }, {
                    indication: 'analgesia',
                    population: 'pediatric',
                    route: 'pr',
                    dose: [
                        {
                            name: 'Load',
                            dose: '40 mg/kg',
                            absoluteMax: '1 g'
                        }, {
                            name: 'Maintenance',
                            dose: '20 mg/kg',
                            absoluteMax: '1 g'
                        }
                    ],
                    description: 'Max 100 mg/kg/day or 4 g/day (whichever is less). Use caution in hepatic impairment.',
                    references: [
                        'Patrick K. Birmingham, AF1-0567, Michael J. Tobin, Dennis M. Fisher, Thomas K. Henthorn, Steven C. Hall, Charles J. Coté; Initial and Subsequent Dosing of Rectal Acetaminophen in Children: A 24-Hour Pharmacokinetic Study of New Dose Recommendations. Anesthesiology 2001; 94:385–389 doi: https://doi.org/10.1097/00000542-200103000-00005'
                    ]
                }
            ],
            preparations: [
                {
                    concentration: '10 mg/mL'
                }
            ]
        }
    } );



    /**
     * Atropine
     */
    mw.calculators.addDrugs( [
        {
            id: 'atropine',
            name: 'Atropine',
            color: 'anticholinergic',
            dosages: [
                {
                    indication: 'bradycardia',
                    population: 'general',
                    dose: {
                        min: '0.5 mg',
                        max: '1 mg',
                        frequency: 'q3-5m'
                    },
                    description: 'Repeat as needed to a maximum total dose of 3 mg'
                }, {
                    indication: 'bradycardia',
                    population: 'pediatric',
                    dose: {
                        min: '10 mcg/kg',
                        max: '20 mcg/kg',
                        absoluteMin: '40 mcg',
                        frequency: 'q3-5m'
                    },
                    description: 'Repeat as needed to a maximum total dose of 1 mg'
                }, {
                    indication: 'acls',
                    population: 'general',
                    dose: {
                        dose: '1 mg',
                        frequency: 'q3-5m'
                    },
                    description: 'Repeat as needed to a maximum total dose of 3 mg'
                }, {
                    indication: 'acls',
                    population: 'pediatric',
                    dose: {
                        dose: '20 mcg/kg',
                        absoluteMin: '100 mcg',
                        absoluteMax: '500 mcg',
                        frequency: 'q3-5m'
                    },
                    description: 'Repeat as needed to a maximum total dose of 1 mg'
                }
            ],
            preparations: [
                {
                    concentration: '0.1 mg/mL'
                }, {
                    concentration: '0.4 mg/mL',
                    default:true
                }
            ]
        }
    ] );



    /**
     * Calcium chloride
     */
    mw.calculators.addDrugs( [
        {
            id: 'calciumChloride',
            name: 'Calcium chloride',
            dosages: [
                {
                    indication: 'hypocalcemia',
                    population: 'general',
                    dose: {
                        min: '500 mg',
                        max: '1 g',
                        duration: '5-10 min'
                    }
                }, {
                    indication: 'hypocalcemia',
                    population: 'pediatric',
                    dose: {
                        min: '10 mg/kg',
                        max: '20 mg/kg',
                        absoluteMax: '1 g',
                        duration: '5-10 min'
                    }
                }
            ],
            preparations: [
                {
                    concentration: '100 mg/mL'
                }
            ],
            description: '<ul><li>Administer via central line</li><li>A 10 mL ampule of calcium chloride 100 mg/mL contains 272 mg of elemental calcium</li></ul>',
            references: [
                'French S, Subauste J, Geraci S. Calcium abnormalities in hospitalized patients. South Med J. 2012 Apr;105(4):231-7. doi: 10.1097/SMJ.0b013e31824e1737. PMID: 22475676.'
            ]
        }
    ] );



    /**
     * Calcium gluconate
     */
    mw.calculators.addDrugs( [
        {
            id: 'calciumGluconate',
            name: 'Calcium gluconate',
            dosages: [
                {
                    indication: 'hypocalcemia',
                    population: 'general',
                    dose: {
                        min: '1 g',
                        max: '2 g',
                        duration: '5-10 min'
                    }
                }, {
                    indication: 'hypocalcemia',
                    population: 'pediatric',
                    dose: {
                        dose: '30 mg/kg',
                        absoluteMax: '2 g',
                        duration: '5-10 min'
                    }
                }
            ],
            preparations: [
                {
                    concentration: '100 mg/mL'
                }
            ],
            description: '<ul><li>Can administer peripherally</li><li>A 10 mL ampule of calcium gluconate 100 mg/mL contains 93 mg of elemental calcium</li></ul>',
            references: [
                'French S, Subauste J, Geraci S. Calcium abnormalities in hospitalized patients. South Med J. 2012 Apr;105(4):231-7. doi: 10.1097/SMJ.0b013e31824e1737. PMID: 22475676.'
            ]
        }
    ] );



    /**
     * Cefazolin
     */
    mw.calculators.addDrugs( {
        cefazolin: {
            name: 'Cefazolin',
            dosages: [
                {
                    indication: 'abxProphylaxis',
                    population: 'general',
                    dose: {
                        dose: '2 g',
                        frequency: 'q4h'
                    }
                }, {
                    indication: 'abxProphylaxis',
                    population: 'general120kg',
                    dose: {
                        dose: '3 g',
                        frequency: 'q4h'
                    }
                }, {
                    indication: 'abxProphylaxis',
                    population: 'pediatric',
                    dose: {
                        dose: '30 mg/kg',
                        frequency: 'q4h'
                    }
                }
            ],
            preparations: [
                {
                    concentration: '1 g/vial'
                }
            ]
        }
    } );



    /**
     * Cisatracurium
     */
    mw.calculators.addDrugs( {
        cisatracurium: {
            name: 'Cisatracurium',
            color: 'neuromuscularBlocker',
            dosages: [
                {
                    indication: 'neuromuscularBlockade',
                    population: 'general',
                    dose: {
                        dose: '0.2 mg/kg'
                    }
                }
            ],
            preparations: [
                {
                    concentration: '2 mg/mL'
                }, {
                    concentration: '20 mg/mL'
                }
            ]
        }
    } );



    /**
     * Dantrolene
     */
    mw.calculators.addDrugs( {
        dantrolene: {
            name: 'Dantrolene',
            dosages: [
                {
                    indication: 'malignantHyperthermia',
                    population: 'general',
                    dose: {
                        dose: '2.5 mg/kg'
                    },
                    description: 'Repeat up to a cumulative dose of 10 mg/kg'
                }
            ],
            preparations: [
                {
                    concentration: '250 mg/vial'
                }, {
                    concentration: '20 mg/vial'
                }
            ]
        }
    } );



    /**
     * Dexmedetomidine
     */
    mw.calculators.addDrugs( {
        dexmedetomidine: {
            name: 'Dexmedetomidine',
            color: 'sedativeHypnotic',
            dosages: [
                {
                    indication: 'mac',
                    population: 'general',
                    dose: [
                        {
                            name: 'Load',
                            dose: '1 mcg/kg',
                            duration: '10 min'
                        }, {
                            name: 'Maintenance',
                            min: '0.2 mcg/kg/hr',
                            max: '1 mcg/kg/hr'
                        }
                    ]
                }
            ],
            preparations: [
                {
                    concentration: '4 mcg/mL'
                }, {
                    concentration: '100 mcg/mL',
                    dilutionRequired: true
                }
            ]
        }
    } );



    /**
     * Dexamethasone
     */
    mw.calculators.addDrugs( [
        {
            id: 'dexamethasone',
            name: 'Dexamethasone',
            dosages: [
                {
                    indication: 'ponv',
                    population: 'general',
                    dose: {
                        min: '4 mg',
                        max: '8 mg'
                    }
                }, {
                    indication: 'ponv',
                    population: 'pediatric',
                    dose: {
                        dose: '0.1 mg/kg',
                        absoluteMax: '10 mg'
                    }
                }
            ],
            preparations: [
                {
                    concentration: '2 mg/mL'
                }
            ]
        }
    ] );



    /**
     * Ephedrine
     */
     mw.calculators.addDrugs( {
        ephedrine: {
            name: 'Ephedrine',
            color: 'cardiovascularAgonist',
            dosages: [
                {
                    indication: 'hypotension',
                    population: 'general',
                    dose: {
                        min: '2.5 mg',
                        max: '25 mg'
                    }
                }, {
                    indication: 'hypotension',
                    population: 'general',
                    route: 'im',
                    dose: {
                        min: '25 mg',
                        max: '50 mg'
                    }
                }, {
                    indication: 'hypotension',
                    population: 'pediatric',
                    dose: {
                        min: '0.02 mg/kg',
                        max: '0.2 mg/kg'
                    }
                }
            ],
            preparations: [
                {
                    concentration: '5 mg/mL'
                }, {
                    concentration: '50 mg/mL'
                }
            ]
        }
    } );



    /**
     * Epinephrine
     */
    mw.calculators.addDrugs( {
        epinephrine: {
            name: 'Epinephrine',
            color: 'epinephrine',
            dosages: [
                {
                    indication: 'acls',
                    population: 'general',
                    dose: {
                        dose: '1 mg',
                        frequency: 'q3-5m'
                    }
                }, {
                    indication: 'acls',
                    population: 'pediatric',
                    dose: {
                        dose: '10 mcg/kg',
                        frequency: 'q3-5m'
                    }
                }, {
                    indication: 'anaphylaxis',
                    population: 'general',
                    dose: [
                        {
                            name: 'Bolus',
                            dose: '10 mcg/kg',
                            frequency: 'q3-5m'
                        }, {
                            name: 'Infusion',
                            min: '0.1 mcg/kg/min',
                            max: '1 mcg/kg/min'
                        }
                    ]
                }, {
                    indication: 'anaphylaxis',
                    population: 'general',
                    route: 'im',
                    dose: {
                        dose: '10 mcg/kg',
                        frequency: 'q5-15m',
                        absoluteMax: '0.5 mg'
                    }
                }
            ],
            preparations: [
                {
                    concentration: '10 mcg/mL'
                }, {
                    concentration: '100 mcg/mL',
                    default: true
                }, {
                    concentration: '160 mcg/mL'
                }, {
                    concentration: '1 mg/mL'
                }
            ]
        }
    } );



    /**
     * Etomidate
     */
    mw.calculators.addDrugs( {
        etomidate: {
            name: 'Etomidate',
            color: 'sedativeHypnotic',
            dosages: [
                {
                    indication: 'generalAnesthesia',
                    population: 'general',
                    dose: {
                        min: '0.2 mg/kg',
                        max: '0.6 mg/kg',
                        weightCalculation: [ 'lbw', 'ibw' ]
                    }
                }
            ],
            preparations: [
                {
                    concentration: '2 mg/mL'
                }
            ]
        }
    } );



    /**
     * Ketamine
     */
    mw.calculators.addDrugs( {
        ketamine: {
            name: 'Ketamine',
            color: 'sedativeHypnotic',
            dosages: [
                {
                    indication: 'generalAnesthesia',
                    population: 'general',
                    dose: {
                        min: '1 mg/kg',
                        max: '2 mg/kg',
                        weightCalculation: [ 'lbw', 'ibw'  ]
                    }
                }, {
                    indication: 'generalAnesthesia',
                    population: 'general',
                    route: 'im',
                    dose: {
                        min: '4 mg/kg',
                        max: '6 mg/kg'
                    }
                }, {
                    indication: 'analgesia',
                    population: 'general',
                    dose: [
                        {
                            name: 'Load (before incision)',
                            min: '0.25 mg/kg',
                            max: '0.5 mg/kg'
                        }, {
                            name: 'Maintenance',
                            min: '0.125 mg/kg',
                            max: '0.25 mg/kg',
                            frequency: 'q30m'
                        }
                    ],
                    description: 'To prevent prolonged recovery, do not administer in last hour of surgery.',
                    references: [
                        'Sabine Himmelseher, Marcel E. Durieux, Richard B. Weiskopf; Ketamine for Perioperative Pain Management. Anesthesiology 2005; 102:211–220 doi: https://doi.org/10.1097/00000542-200501000-00030'
                    ]
                }
            ],
            preparations: [
                {
                    concentration: '10 mg/mL'
                }, {
                    concentration: '50 mg/mL'
                }, {
                    concentration: '100 mg/mL'
                }
            ]
        }
    } );



    /**
     * Ketorolac
     */
    mw.calculators.addDrugs( [
        {
            id: 'ketorolac',
            name: 'Ketorolac',
            dosages: [
                {
                    indication: 'analgesia',
                    population: 'general',
                    dose: {
                        min: '10 mg',
                        max: '30 mg'
                    },
                    description: 'A 10 mg dose of ketorolac is as effective for acute pain control as a 15 or 30 mg dose<sup>1</sup>',
                    references: [
                        'Motov S, Yasavolian M, Likourezos A, Pushkar I, Hossain R, Drapkin J, Cohen V, Filk N, Smith A, Huang F, Rockoff B, Homel P, Fromm C. Comparison of Intravenous Ketorolac at Three Single-Dose Regimens for Treating Acute Pain in the Emergency Department: A Randomized Controlled Trial. Ann Emerg Med. 2017 Aug;70(2):177-184. doi: 10.1016/j.annemergmed.2016.10.014. Epub 2016 Dec 16. PMID: 27993418.'
                    ]
                }, {
                    indication: 'analgesia',
                    population: 'pediatric',
                    dose: {
                        min: '0.5 mg/kg',
                        max: '1 mg/kg',
                        absoluteMax: '30 mg'
                    }
                }
            ],
            preparations: [
                {
                    concentration: '15 mg/mL'
                }, {
                    concentration: '30 mg/mL',
                    default: true
                }
            ]
        }
    ] );



    /**
     * Lidocaine
     */
    mw.calculators.addDrugs( {
        lidocaine: {
            name: 'Lidocaine',
            color: 'localAnesthetic',
            dosages: [
                {
                    indication: 'intubation',
                    population: 'general',
                    dose: {
                        dose: '1 mg/kg'
                    }
                }
            ],
            preparations: [
                {
                    concentration: '1 pct'
                }, {
                    concentration: '2 pct'
                }
            ]
        }
    } );



    /**
     * Midazolam
     */
    mw.calculators.addDrugs( {
        midazolam: {
            name: 'Midazolam',
            color: 'benzodiazepine',
            dosages: [
                {
                    indication: 'anxiolysis',
                    population: 'general',
                    dose: {
                        min: '0.01 mg/kg',
                        max: '0.03 mg/kg'
                    }
                }, {
                    indication: 'anxiolysis',
                    population: 'general',
                    route: 'im',
                    dose: {
                        min: '0.07 mg/kg',
                        max: '0.08 mg/kg'
                    }
                }, {
                    indication: 'anxiolysis',
                    population: 'general',
                    route: 'po',
                    dose: {
                        dose: '0.5 mg/kg',
                        absoluteMax: '20 mg'
                    }
                }, {
                    indication: 'generalAnesthesia',
                    population: 'general',
                    dose: {
                        min: '0.1 mg/kg',
                        max: '0.3 mg/kg',
                        weightCalculation: [ 'lbw', 'ibw' ]
                    }
                }
            ],
            preparations: [
                {
                    concentration: '1 mg/mL'
                }, {
                    concentration: '5 mg/mL'
                }
            ]
        }
    } );



    /**
     * Neostigmine
     */
    mw.calculators.addDrugs( {
        neostigmine: {
            name: 'Neostigmine',
            color: 'neuromuscularBlockerReversal',
            dosages: [
                {
                    indication: 'neuromuscularBlockadeReversal',
                    population: 'general',
                    dose: {
                        min: '0.03 mg/kg',
                        max: '0.07 mg/kg',
                        absoluteMax: '5 mg'
                    },
                    description: 'For each 1 mg of neostigmine, give 0.2 mg of glycopyrrolate to avoid bradycardia'
                }
            ],
            preparations: [
                {
                    concentration: '0.5 mg/mL'
                }, {
                    concentration: '1 mg/mL'
                }
            ]
        }
    } );



    /**
     * Ondansetron
     */
    mw.calculators.addDrugs( {
        ondansetron: {
            name: 'Ondansetron',
            dosages: [
                {
                    indication: 'ponv',
                    population: 'general',
                    dose: {
                        dose: '4 mg'
                    }
                }, {
                    indication: 'ponv',
                    population: 'pediatric',
                    dose: {
                        dose: '0.1 mg/kg',
                        absoluteMax: '4 mg'
                    }
                }
            ],
            preparations: [
                {
                    concentration: '2 mg/mL'
                }
            ]
        }
    } );



    /**
     * Phenylephrine
     */
    mw.calculators.addDrugs( {
        phenylephrine: {
            name: 'Phenylephrine',
            color: 'cardiovascularAgonist',
            dosages: [
                {
                    indication: 'hypotension',
                    population: 'general',
                    dose: [
                        {
                            name: 'Bolus',
                            min: '1 mcg/kg',
                            max: '2 mcg/kg'
                        }, {
                            name: 'Infusion',
                            min: '0.25 mcg/kg/min',
                            max: '1 mcg/kg/min'
                        }
                    ]
                }, {
                    indication: 'hypotension',
                    population: 'pediatric',
                    dose: [
                        {
                            name: 'Bolus',
                            min: '0.5 mcg/kg',
                            max: '1 mcg/kg'
                        }, {
                            name: 'Infusion',
                            min: '0.1 mcg/kg/min',
                            max: '0.5 mcg/kg/min'
                        }
                    ]
                }
            ],
            preparations: [
                {
                    concentration: '10 mcg/mL'
                }, {
                    concentration: '100 mcg/mL',
                    default: true
                }, {
                    concentration: '160 mcg/mL'
                }, {
                    concentration: '10 mg/mL',
                    dilutionRequired: true
                }
            ]
        }
    } );



    /**
     * Propofol
     */
    mw.calculators.addDrugs( {
        propofol: {
            name: 'Propofol',
            color: 'sedativeHypnotic',
            dosages: [
                {
                    indication: 'generalAnesthesia',
                    population: 'general',
                    dose: [
                        {
                            name: 'Induction',
                            min: '1 mg/kg',
                            max: '2.5 mg/kg',
                            weightCalculation: [ 'lbw', 'ibw' ]
                        }, {
                            name: 'Maintenance',
                            min: '100 mcg/kg/min',
                            max: '200 mcg/kg/min'
                        }
                    ]
                }, {
                    indication: 'generalAnesthesia',
                    population: 'pediatric',
                    dose: [
                        {
                            name: 'Induction',
                            min: '2.5 mg/kg',
                            max: '3.5 mg/kg',
                            weightCalculation: [ 'lbw', 'ibw' ]
                        }, {
                            name: 'Maintenance',
                            min: '125 mcg/kg/min',
                            max: '300 mcg/kg/min'
                        }
                    ]
                }, {
                    indication: 'generalAnesthesia',
                    population: 'geriatric',
                    dose: [
                        {
                            name: 'Induction',
                            min: '1 mg/kg',
                            max: '1.5 mg/kg',
                            weightCalculation: [ 'lbw', 'ibw' ]
                        }, {
                            name: 'Maintenance',
                            min: '50 mcg/kg/min',
                            max: '100 mcg/kg/min'
                        }
                    ]
                }, {
                    indication: 'mac',
                    population: 'general',
                    dose: {
                        min: '25 mcg/kg/min',
                        max: '75 mcg/kg/min'
                    }
                }
            ],
            preparations: [
                {
                    concentration: '10 mg/mL'
                }
            ]
        }
    } );



    /**
     * Remifentanil
     */
    mw.calculators.addDrugs( {
        remifentanil: {
            name: 'Remifentanil',
            color: 'opioid',
            dosages: [
                {
                    indication: 'tiva',
                    population: 'general',
                    dose: [
                        {
                            name: 'Load',
                            min: '1 mcg/kg',
                            max: '2 mcg/kg',
                            weightCalculation: [ 'lbw', 'ibw' ]
                        }, {
                            name: 'Maintenance',
                            min: '0.1 mcg/kg/min',
                            max: '1 mcg/kg/min'
                        }
                    ]
                }
            ],
            preparations: [
                {
                    concentration: '50 mcg/mL'
                }, {
                    concentration: '1 mg/vial',
                    dilutionRequired: true
                }, {
                    concentration: '2 mg/vial',
                    dilutionRequired: true
                }
            ]
        }
    } );



    /**
     * Rocuronium
     */
    mw.calculators.addDrugs( {
        rocuronium: {
            name: 'Rocuronium',
            color: 'neuromuscularBlocker',
            dosages: [
                {
                    indication: 'neuromuscularBlockade',
                    population: 'general',
                    dose: [
                        {
                            name: 'Standard',
                            dose: '0.6 mg/kg'
                        }, {
                            name: 'Rapid sequence',
                            dose: '1.2 mg/kg'
                        }
                    ]
                }
            ],
            preparations: [
                {
                    concentration: '10 mg/mL'
                }
            ]
        }
    } );



    /**
     * Succinylcholine
     */
    mw.calculators.addDrugs( {
        succinylcholine: {
            name: 'Succinylcholine',
            color: 'succinylcholine',
            dosages: [
                {
                    indication: 'neuromuscularBlockade',
                    population: 'general',
                    dose: {
                        min: '1 mg/kg',
                        max: '1.5 mg/kg'
                    }
                }, {
                    indication: 'neuromuscularBlockade',
                    population: 'general',
                    route: 'im',
                    dose: {
                        min: '3 mg/kg',
                        max: '5 mg/kg'
                    }
                }
            ],
            preparations: [
                {
                    concentration: '20 mg/mL'
                }, {
                    concentration: '100 mg/mL'
                }
            ]
        }
    } );



    /**
     * Sufentanil
     */
    mw.calculators.addDrugs( {
        sufentanil: {
            name: 'Sufentanil',
            color: 'opioid',
            dosages: [
                {
                    indication: 'tiva',
                    population: 'general',
                    dose: [
                        {
                            name: 'Load',
                            min: '0.25 mcg/kg',
                            max: '2 mcg/kg',
                            weightCalculation: [ 'lbw', 'ibw' ]
                        }, {
                            name: 'Maintenance',
                            min: '0.5 mcg/kg/hr',
                            max: '1.5 mcg/kg/hr'
                        }
                    ]
                }
            ],
            preparations: [
                {
                    concentration: '5 mcg/mL'
                }, {
                    concentration: '50 mcg/mL'
                }
            ]
        }
    } );



    /**
     * Sugammadex
     */
    mw.calculators.addDrugs( {
        sugammadex: {
            name: 'Sugammadex',
            color: 'neuromuscularBlockerReversal',
            dosages: [
                {
                    indication: 'neuromuscularBlockadeReversal',
                    population: 'general',
                    dose: {
                        min: '2 mg/kg',
                        max: '16 mg/kg'
                    },
                    description: '<ul><li>&ge;2 twitches on TOF: 2 mg/kg</li><li>1-2 posttetanic twitches: 4 mg/kg</li><li>Immediate reversal: 16 mg/kg</li></ul>'
                }
            ],
            preparations: [
                {
                    concentration: '100 mg/mL'
                }
            ]
        }
    } );



    /**
     * Vasopressin
     */
    mw.calculators.addDrugs( {
        ephedrine: {
            name: 'Vasopressin',
            color: 'cardiovascularAgonist',
            dosages: [
                {
                    indication: 'hypotension',
                    population: 'general',
                    dose: [
                        {
                            name: 'Bolus',
                            min: '0.5 units',
                            max: '1 unit'
                        }, {
                            name: 'Infusion',
                            min: '0.01 units/min',
                            max: '0.07 units/min'
                        }
                    ],
                    description: 'Use caution with sustained infusions >0.04 units/min which can cause cardiac and splanchnic ischemia',
                    references: [
                        'Hollenberg SM. Vasoactive drugs in circulatory shock. Am J Respir Crit Care Med. 2011 Apr 1;183(7):847-55. doi: 10.1164/rccm.201006-0972CI. Epub 2010 Nov 19. PMID: 21097695.'
                    ]
                }, {
                    indication: 'hypotension',
                    population: 'pediatric',
                    dose: [
                        {
                            name: 'Bolus',
                            min: '0.02 mg/kg',
                            max: '0.2 mg/kg'
                        }, {
                            name: 'Infusion',
                            min: '0.0002 units/kg/min',
                            max: '0.008 units/kg/min'
                        }
                    ],
                    references: [
                        'Choong K, Kissoon N. Vasopressin in pediatric shock and cardiac arrest. Pediatr Crit Care Med. 2008 Jul;9(4):372-9. doi: 10.1097/PCC.0b013e318172d7c8. PMID: 18496412.'
                    ]
                }, {
                    indication: 'acls',
                    population: 'general',
                    dose: {
                        dose: '20 units'
                    }
                }, {
                    indication: 'acls',
                    population: 'pediatric',
                    dose: {
                        min: '0.4 units/kg',
                        max: '1 units/kg',
                        absoluteMax: '40 units'
                    }
                }
            ],
            preparations: [
                {
                    concentration: '1 units/mL'
                }, {
                    concentration: '20 units/mL',
                    default: true
                }
            ]
        }
    } );



    /**
     * Vecuronium
     */
    mw.calculators.addDrugs( {
        vecuronium: {
            name: 'Vecuronium',
            color: 'neuromuscularBlocker',
            dosages: [
                {
                    indication: 'neuromuscularBlockade',
                    population: 'general',
                    dose: [
                        {
                            name: 'Standard',
                            dose: '0.1 mg/kg'
                        }, {
                            name: 'Rapid sequence',
                            dose: '1.2 mg/kg'
                        }
                    ]
                }
            ],
            preparations: [
                {
                    concentration: '10 mg/vial'
                }
            ]
        }
    } );
}() );