MediaWiki:Gadget-calculator-drugs-core.js
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Revision as of 17:30, 20 August 2021 by Chris Rishel (talk | contribs)
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/** * @author Chris Rishel */ ( function() { var DEFAULT_DRUG_COLOR = 'default'; var DEFAULT_DRUG_POPULATION = 'general'; var DEFAULT_DRUG_ROUTE = 'iv'; mw.calculators.isValueDependent = function( value, variableId ) { // This may need generalized to support other variables in the future if( variableId === 'weight' ) { return value && value.formatUnits().match( /\/[\s(]*?kg/ ); } else { throw new Error( 'Dependence "' + variableId + '" not supported by isValueDependent' ); } }; /** * Define units */ mw.calculators.addUnitsBases( { concentration: { toString: function( units ) { units = units.replace( ' pct', '%' ); units = units.replace( 'ug', 'mcg' ); return units; } }, mass: { toString: function( units ) { units = units.replace( 'ug', 'mcg' ); return units; } } } ); mw.calculators.addUnits( { pct: { baseName: 'concentration', definition: '10 mg/mL' }, vial: { baseName: 'volume' } } ); /** * DrugColor */ mw.calculators.drugColors = {}; mw.calculators.addDrugColors = function( drugColorData ) { var drugColors = mw.calculators.createCalculatorObjects( 'DrugColor', drugColorData ); for( var drugColorId in drugColors ) { mw.calculators.drugColors[ drugColorId ] = drugColors[ drugColorId ]; } }; mw.calculators.getDrugColor = function( drugColorId ) { if( mw.calculators.drugColors.hasOwnProperty( drugColorId ) ) { return mw.calculators.drugColors[ drugColorId ]; } else { return null; } }; /** * Class DrugColor * @param {Object} propertyValues * @returns {mw.calculators.objectClasses.DrugColor} * @constructor */ mw.calculators.objectClasses.DrugColor = function( propertyValues ) { var properties = { required: [ 'id' ], optional: [ 'parentColor', 'primaryColor', 'highlightColor', 'striped' ] }; mw.calculators.objectClasses.CalculatorObject.call( this, properties, propertyValues ); this.parentColor = this.parentColor || this.id === DEFAULT_DRUG_COLOR ? this.parentColor : DEFAULT_DRUG_COLOR; }; mw.calculators.objectClasses.DrugColor.prototype = Object.create( mw.calculators.objectClasses.CalculatorObject.prototype ); mw.calculators.objectClasses.DrugColor.prototype.getParentDrugColor = function() { if( !this.parentColor ) { return null; } var parentDrugColor = mw.calculators.getDrugColor( this.parentColor ); if( !parentDrugColor ) { throw new Error( 'Parent drug color "' + this.parentColor + '" not found for drug color "' + this.id + '"' ); } return parentDrugColor; }; mw.calculators.objectClasses.DrugColor.prototype.getHighlightColor = function() { if( this.highlightColor ) { return this.highlightColor; } else if( this.parentColor ) { return this.getParentDrugColor().getHighlightColor(); } }; mw.calculators.objectClasses.DrugColor.prototype.getPrimaryColor = function() { if( this.primaryColor ) { return this.primaryColor; } else if( this.parentColor ) { return this.getParentDrugColor().getPrimaryColor(); } }; mw.calculators.objectClasses.DrugColor.prototype.isStriped = function() { if( this.striped !== null ) { return this.striped; } else if( this.parentColor ) { return this.getParentDrugColor().isStriped(); } }; /** * DrugPopulation */ mw.calculators.drugPopulations = {}; mw.calculators.addDrugPopulations = function( drugPopulationData ) { var drugPopulations = mw.calculators.createCalculatorObjects( 'DrugPopulation', drugPopulationData ); for( var drugPopulationId in drugPopulations ) { mw.calculators.drugPopulations[ drugPopulationId ] = drugPopulations[ drugPopulationId ]; } }; mw.calculators.getDrugPopulation = function( drugPopulationId ) { if( mw.calculators.drugPopulations.hasOwnProperty( drugPopulationId ) ) { return mw.calculators.drugPopulations[ drugPopulationId ]; } else { return null; } }; /** * Class DrugPopulation * @param {Object} propertyValues * @returns {mw.calculators.objectClasses.DrugPopulation} * @constructor */ mw.calculators.objectClasses.DrugPopulation = function( propertyValues ) { var properties = { required: [ 'id', 'name' ], optional: [ 'abbreviation', 'variables' ] }; mw.calculators.objectClasses.CalculatorObject.call( this, properties, propertyValues ); if( this.variables ) { for( var variableId in this.variables ) { if( !mw.calculators.getVariable( variableId ) ) { throw new Error( 'DrugPopulation variable "' + variableId + '" not defined' ); } this.variables[ variableId ].min = this.variables[ variableId ].hasOwnProperty( 'min' ) ? math.unit( this.variables[ variableId ].min ) : null; this.variables[ variableId ].max = this.variables[ variableId ].hasOwnProperty( 'max' ) ? math.unit( this.variables[ variableId ].max ) : null; } } else { this.variables = {}; } }; mw.calculators.objectClasses.DrugPopulation.prototype = Object.create( mw.calculators.objectClasses.CalculatorObject.prototype ); mw.calculators.objectClasses.DrugPopulation.prototype.getCalculationData = function() { var inputData = new mw.calculators.objectClasses.CalculationData(); for( var variableId in this.variables ) { inputData.variables.required.push( variableId ); } return inputData; }; mw.calculators.objectClasses.DrugPopulation.prototype.getCalculationDataScore = function( dataValues ) { // A return value of -1 indicates the data did not match the population definition for( var variableId in this.variables ) { if( !dataValues.hasOwnProperty( variableId ) ) { return -1; } if( this.variables[ variableId ].min && ( !dataValues[ variableId ] || !math.largerEq( dataValues[ variableId ], this.variables[ variableId ].min ) ) ) { return -1; } if( this.variables[ variableId ].max && ( !dataValues[ variableId ] || !math.smallerEq( dataValues[ variableId ], this.variables[ variableId ].max ) ) ) { return -1; } } // If the data matches the population definition, the score corresponds to the number of variables in the // population definition. This should roughly correspond to the specificity of the population. return Object.keys( this.variables ).length; }; mw.calculators.objectClasses.DrugPopulation.prototype.toString = function() { return mw.calculators.isMobile() && this.abbreviation ? this.abbreviation : this.name; }; /** * DrugRoute */ mw.calculators.drugRoutes = {}; mw.calculators.addDrugRoutes = function( drugRouteData ) { var drugRoutes = mw.calculators.createCalculatorObjects( 'DrugRoute', drugRouteData ); for( var drugRouteId in drugRoutes ) { mw.calculators.drugRoutes[ drugRouteId ] = drugRoutes[ drugRouteId ]; } }; mw.calculators.getDrugRoute = function( drugRouteId ) { if( mw.calculators.drugRoutes.hasOwnProperty( drugRouteId ) ) { return mw.calculators.drugRoutes[ drugRouteId ]; } else { return null; } }; /** * Class DrugRoute * @param {Object} propertyValues * @returns {mw.calculators.objectClasses.DrugRoute} * @constructor */ mw.calculators.objectClasses.DrugRoute = function( propertyValues ) { var properties = { required: [ 'id', 'name' ], optional: [ 'abbreviation', 'default' ] }; mw.calculators.objectClasses.CalculatorObject.call( this, properties, propertyValues ); }; mw.calculators.objectClasses.DrugRoute.prototype = Object.create( mw.calculators.objectClasses.CalculatorObject.prototype ); mw.calculators.objectClasses.DrugRoute.prototype.toString = function() { return mw.calculators.isMobile() && this.abbreviation ? this.abbreviation : this.name; }; /** * DrugIndication */ mw.calculators.drugIndications = {}; mw.calculators.addDrugIndications = function( drugIndicationData ) { var drugIndications = mw.calculators.createCalculatorObjects( 'DrugIndication', drugIndicationData ); for( var drugIndicationId in drugIndications ) { mw.calculators.drugIndications[ drugIndicationId ] = drugIndications[ drugIndicationId ]; } }; mw.calculators.getDrugIndication = function( drugIndicationId ) { if( mw.calculators.drugIndications.hasOwnProperty( drugIndicationId ) ) { return mw.calculators.drugIndications[ drugIndicationId ]; } else { return null; } }; /** * Class DrugIndication * @param {Object} propertyValues * @returns {mw.calculators.objectClasses.DrugIndication} * @constructor */ mw.calculators.objectClasses.DrugIndication = function( propertyValues ) { var properties = { required: [ 'id', 'name' ], optional: [ 'abbreviation', 'default' ] }; mw.calculators.objectClasses.CalculatorObject.call( this, properties, propertyValues ); }; mw.calculators.objectClasses.DrugIndication.prototype = Object.create( mw.calculators.objectClasses.CalculatorObject.prototype ); mw.calculators.objectClasses.DrugIndication.prototype.toString = function() { return mw.calculators.isMobile() && this.abbreviation ? this.abbreviation : this.name; }; /** * Drug */ mw.calculators.drugs = {}; mw.calculators.addDrugs = function( drugData ) { var drugs = mw.calculators.createCalculatorObjects( 'Drug', drugData ); for( var drugId in drugs ) { mw.calculators.drugs[ drugId ] = drugs[ drugId ]; var drugDosageCalculationId = mw.calculators.getDrugDosageCalculationId( drugId ); var drugDosageCalculation = mw.calculators.getCalculation( drugDosageCalculationId ); if( !drugDosageCalculation ) { var calculationData = {}; calculationData[ drugDosageCalculationId ] = { calculate: mw.calculators.objectClasses.DrugDosageCalculation.prototype.calculate, drug: drugId, type: 'drug' }; mw.calculators.addCalculations( calculationData, 'DrugDosageCalculation' ); drugDosageCalculation = mw.calculators.getCalculation( drugDosageCalculationId ); } drugDosageCalculation.setDependencies(); } }; mw.calculators.addDrugDosages = function( drugId, drugDosageData ) { var drug = mw.calculators.getDrug( drugId ); if( !drug ) { throw new Error( 'DrugDosage references drug "' + drugId + '" which is not defined' ); } drug.addDosages( drugDosageData ); // Update calculation dependencies var drugDosageCalculation = mw.calculators.getCalculation( mw.calculators.getDrugDosageCalculationId( drugId ) ); drugDosageCalculation.updateVariables(); drugDosageCalculation.setDependencies(); }; mw.calculators.getDrug = function( drugId ) { if( mw.calculators.drugs.hasOwnProperty( drugId ) ) { return mw.calculators.drugs[ drugId ]; } else { return null; } }; /** * Class Drug * @param {Object} propertyValues * @returns {mw.calculators.objectClasses.Drug} * @constructor */ mw.calculators.objectClasses.Drug = function( propertyValues ) { mw.calculators.objectClasses.CalculatorObject.call( this, this.getProperties(), propertyValues ); if( !this.color ) { this.color = DEFAULT_DRUG_COLOR; } var color = mw.calculators.getDrugColor( this.color ); if( !color ) { throw new Error( 'Invalid drug color "' + this.color + '" for drug "' + this.id + '"' ); } this.color = color; if( this.preparations ) { var preparationData = this.preparations; this.preparations = []; this.addPreparations( preparationData ); } else { this.preparations = []; } if( this.dosages ) { var dosageData = this.dosages; this.dosages = []; this.addDosages( dosageData ); } else { this.dosages = []; } }; mw.calculators.objectClasses.Drug.prototype = Object.create( mw.calculators.objectClasses.CalculatorObject.prototype ); mw.calculators.objectClasses.Drug.prototype.addDosages = function( dosageData ) { var dosages = mw.calculators.createCalculatorObjects( 'DrugDosage', dosageData ); for( var dosageId in dosages ) { dosages[ dosageId ].id = this.dosages.length; this.dosages.push( dosages[ dosageId ] ); } }; mw.calculators.objectClasses.Drug.prototype.addPreparations = function( preparationData ) { var preparations = mw.calculators.createCalculatorObjects( 'DrugPreparation', preparationData ); for( var preparationId in preparations ) { preparations[ preparationId ].id = this.preparations.length; this.preparations.push( preparations[ preparationId ] ); } }; mw.calculators.objectClasses.Drug.prototype.getIndications = function() { var indications = []; for( var iDosage in this.dosages ) { if( this.dosages[ iDosage ].indication ) { indications.push( this.dosages[ iDosage ].indication ); } } return indications.filter( mw.calculators.uniqueValues ); }; mw.calculators.objectClasses.Drug.prototype.getPopulations = function( indicationId ) { var populations = []; for( var iDosage in this.dosages ) { if( this.dosages[ iDosage ].population && ( !indicationId || ( this.dosages[ iDosage ].indication && this.dosages[ iDosage ].indication.id === indicationId ) ) ) { populations.push( this.dosages[ iDosage ].population ); } } return populations.filter( mw.calculators.uniqueValues ); }; mw.calculators.objectClasses.Drug.prototype.getRoutes = function( indicationId ) { var routes = []; for( var iDosage in this.dosages ) { if( this.dosages[ iDosage ].route && ( !indicationId || ( this.dosages[ iDosage ].indication && this.dosages[ iDosage ].indication.id === indicationId ) ) ) { routes.push( this.dosages[ iDosage ].route ); } } return routes.filter( mw.calculators.uniqueValues ); }; mw.calculators.objectClasses.Drug.prototype.getPreparations = function() { return this.preparations.filter( mw.calculators.uniqueValues ); }; mw.calculators.objectClasses.Drug.prototype.getProperties = function() { return { required: [ 'id', 'name' ], optional: [ 'color', 'dosages', 'preparations' ] }; }; /** * DrugPreparation */ mw.calculators.addDrugPreparations = function( drugId, drugPreparationData ) { var drug = mw.calculators.getDrug( drugId ); if( !drug ) { throw new Error( 'DrugPreparation references drug "' + drugId + '" which is not defined' ); } drug.addPreparations( drugPreparationData ); var drugDosageCalculation = mw.calculators.getCalculation( mw.calculators.getDrugDosageCalculationId( drugId ) ); drugDosageCalculation.recalculate(); }; /** * Class DrugPreparation * @param {Object} propertyValues * @returns {mw.calculators.objectClasses.DrugPreparation} * @constructor */ mw.calculators.objectClasses.DrugPreparation = function( propertyValues ) { var properties = { required: [ 'id', 'concentration' ], optional: [ 'default', 'dilutionRequired', 'commonDilution' ] }; mw.calculators.objectClasses.CalculatorObject.call( this, properties, propertyValues ); this.concentration = this.concentration.replace( 'mcg', 'ug' ); this.concentration = math.unit( this.concentration ); }; mw.calculators.objectClasses.DrugPreparation.prototype = Object.create( mw.calculators.objectClasses.CalculatorObject.prototype ); mw.calculators.objectClasses.DrugPreparation.prototype.getVolumeUnits = function() { // The units of concentration will always be of the form "mass / volume" // The regular expression matches all text leading up to the volume units return mw.calculators.getUnitsByBase( this.concentration ).volume; }; mw.calculators.objectClasses.DrugPreparation.prototype.toString = function() { return mw.calculators.getValueString( this.concentration ); }; /** * Class DrugDosage * @param {Object} propertyValues * @returns {mw.calculators.objectClasses.DrugDosage} * @constructor */ mw.calculators.objectClasses.DrugDosage = function( propertyValues ) { mw.calculators.objectClasses.CalculatorObject.call( this, this.getProperties(), propertyValues ); var drugIndication = mw.calculators.getDrugIndication( this.indication ); if( !drugIndication ) { throw new Error( 'Invalid indication "' + this.indication + '" for drug dosage' ); } this.indication = drugIndication; this.population = this.population ? this.population : DEFAULT_DRUG_POPULATION; var drugPopulation = mw.calculators.getDrugPopulation( this.population ); if( !drugPopulation ) { throw new Error( 'Invalid population "' + this.population + '" for drug dosage' ); } this.population = drugPopulation; this.route = this.route ? this.route : DEFAULT_DRUG_ROUTE; var drugRoute = mw.calculators.getDrugRoute( this.route ); if( !drugRoute ) { throw new Error( 'Invalid route "' + this.route + '" for drug dosage' ); } this.route = drugRoute; // Add the dose objects to the drug var drugDoseData = this.dose; this.dose = []; this.addDoses( drugDoseData ); }; mw.calculators.objectClasses.DrugDosage.prototype = Object.create( mw.calculators.objectClasses.CalculatorObject.prototype ); mw.calculators.objectClasses.DrugDosage.prototype.addDoses = function( drugDoseData ) { // Each dosage can have one or more associated doses. Ensure this value is an array. if( !Array.isArray( drugDoseData ) ) { drugDoseData = [ drugDoseData ]; } var doses = mw.calculators.createCalculatorObjects( 'DrugDose', drugDoseData ); for( var doseId in doses ) { doses[ doseId ].id = this.dose.length; this.dose.push( doses[ doseId ] ); } }; mw.calculators.objectClasses.DrugDosage.prototype.getCalculationData = function() { var inputData = new mw.calculators.objectClasses.CalculationData(); inputData = inputData.merge( this.population.getCalculationData() ); for( var iDose in this.dose ) { inputData = inputData.merge( this.dose[ iDose ].getCalculationData() ); } return inputData; }; mw.calculators.objectClasses.DrugDosage.prototype.getProperties = function() { return { required: [ 'dose', 'id', 'indication' ], optional: [ 'description', 'population', 'route' ] }; }; mw.calculators.objectClasses.DrugDosage.prototype.hasInfo = function() { return this.description; }; /** * Class DrugDose * @param {Object} propertyValues * @returns {mw.calculators.objectClasses.DrugDose} * @constructor */ mw.calculators.objectClasses.DrugDose = function( propertyValues ) { mw.calculators.objectClasses.CalculatorObject.call( this, this.getProperties(), propertyValues ); if( this.weightCalculation ) { var weightCalculationIds = this.weightCalculation; // weightCalculation property will contain references to the actual objects, so reinitialize this.weightCalculation = []; if( !Array.isArray( weightCalculationIds ) ) { weightCalculationIds = [ weightCalculationIds ]; } for( var iWeightCalculation in weightCalculationIds ) { var weightCalculationId = weightCalculationIds[ iWeightCalculation ]; var weightCalculation = mw.calculators.getCalculation( weightCalculationId ); if( !weightCalculation ) { throw new Error( 'Drug dose references weight calculation "' + weightCalculationId + '" which is not defined' ); } this.weightCalculation.push( weightCalculation ); } } else { this.weightCalculation = []; } var mathProperties = this.getMathProperties(); var isWeightDependent = false; for( var iMathProperty in mathProperties ) { var mathProperty = mathProperties[ iMathProperty ]; if( this[ mathProperty ] ) { // TODO consider making a UnitsBase.weight.fromString() this[ mathProperty ] = this[ mathProperty ].replace( 'kg', 'kgwt' ); this[ mathProperty ] = this[ mathProperty ].replace( 'mcg', 'ug' ); this[ mathProperty ] = math.unit( this[ mathProperty ] ); if( mw.calculators.isValueDependent( this[ mathProperty ], 'weight' ) ) { isWeightDependent = true; } } else { this[ mathProperty ] = null; } } if( isWeightDependent ) { // Default is tbw this.weightCalculation.push( mw.calculators.getCalculation( 'tbw' ) ); } }; mw.calculators.objectClasses.DrugDose.prototype = Object.create( mw.calculators.objectClasses.CalculatorObject.prototype ); mw.calculators.objectClasses.DrugDose.prototype.getAdministration = function() { var administration = ''; if( this.frequency ) { administration += administration ? ' ' : ''; administration += this.frequency; } if( this.duration ) { administration += administration ? ' ' : ''; administration += 'over ' + this.duration; } return administration; }; mw.calculators.objectClasses.DrugDose.prototype.getCalculationData = function() { var calculationData = new mw.calculators.objectClasses.CalculationData(); for( var iWeightCalculation in this.weightCalculation ) { calculationData.calculations.optional.push( this.weightCalculation[ iWeightCalculation ].id ); } return calculationData; }; mw.calculators.objectClasses.DrugDose.prototype.getMathProperties = function() { return [ 'dose', 'min', 'max', 'absoluteMax' ]; }; mw.calculators.objectClasses.DrugDose.prototype.getProperties = function() { return { required: [ 'id' ], optional: [ 'absoluteMax', 'dose', 'duration', 'frequency', 'min', 'max', 'name', 'weightCalculation' ] }; }; mw.calculators.getDrugDosageCalculationId = function( drugId ) { return 'drugDosages-' + drugId; }; /** * Class DrugDosageCalculation * @param {Object} propertyValues * @returns {mw.calculators.objectClasses.DrugDosageCalculation} * @constructor */ mw.calculators.objectClasses.DrugDosageCalculation = function( propertyValues ) { mw.calculators.objectClasses.CalculatorObject.call( this, this.getProperties(), propertyValues ); this.initialize(); }; mw.calculators.objectClasses.DrugDosageCalculation.prototype = Object.create( mw.calculators.objectClasses.AbstractCalculation.prototype ); mw.calculators.objectClasses.DrugDosageCalculation.prototype.calculate = function( data ) { var value = { dosageId: null, message: null, population: null, preparation: data.preparation, dose: [] }; if( !data.drug.dosages.length ) { value.message = 'No dose data'; return value; } // Determine which dosage to use var populationScores = []; for( var iDosage in data.drug.dosages ) { var drugDosage = data.drug.dosages[ iDosage ]; // If the indication and route do not match, set the score to -1 var populationScore = drugDosage.indication.id === data.indication.id && drugDosage.route.id === data.route.id ? drugDosage.population.getCalculationDataScore( data ) : -1; populationScores.push( populationScore ); } var maxPopulationScore = Math.max.apply( null, populationScores ); if( maxPopulationScore < 0 ) { value.message = 'No dose data for indication "' + String( data.indication ) + '" and route "' + String( data.route ) + '"'; return value; } // If there is more than one dosage with the same score, take the first. // This allows the data editor to decide which is most important. value.dosageId = populationScores.indexOf( maxPopulationScore ); var dosage = data.drug.dosages[ value.dosageId ]; // A dosage may contain multiple doses (e.g. induction and maintenance) for( var iDose in dosage.dose ) { var dose = dosage.dose[ iDose ]; var mathProperties = dose.getMathProperties(); var weightCalculation = null; var weightValue = null; // data.weightCalculation should be in order of preference, so take the first non-null value for( var iWeightCalculation in dose.weightCalculation ) { if( dose.weightCalculation[ iWeightCalculation ].value !== null ) { weightCalculation = dose.weightCalculation[ iWeightCalculation ]; weightValue = dose.weightCalculation[ iWeightCalculation ].value; break; } } // Initialize value properties for dose value.dose[ iDose ] = { massPerWeight: {}, mass: {}, volume: {}, weightCalculation: weightCalculation ? weightCalculation : null }; var massUnits; var volumeUnits; for( var iMathProperty in mathProperties ) { var mathProperty = mathProperties[ iMathProperty ]; var doseValue = dose[ mathProperty ]; if( doseValue ) { var doseUnitsByBase = mw.calculators.getUnitsByBase( doseValue ); if( doseUnitsByBase.hasOwnProperty( 'weight' ) ) { value.dose[ iDose ].massPerWeight[ mathProperty ] = doseValue; if( weightValue ) { massUnits = doseUnitsByBase.mass; if( doseUnitsByBase.hasOwnProperty( 'time' ) ) { massUnits += '/' + doseUnitsByBase.time; } // For whatever reason math.format will simplify the units, but math.formatUnits will not // as a hack, we recreate a new unit value with the correct formatting of the result value.dose[ iDose ].mass[ mathProperty ] = math.unit( math.multiply( doseValue, weightValue ).format() ).to( massUnits ); } } else { value.dose[ iDose ].mass[ mathProperty ] = doseValue; } if( data.preparation && value.dose[ iDose ].mass[ mathProperty ] ) { // Same hack as above to get units to simplify correctly var preparationUnitsByBase = mw.calculators.getUnitsByBase( data.preparation.concentration ); volumeUnits = preparationUnitsByBase.volume; if( doseUnitsByBase.hasOwnProperty( 'time' ) ) { volumeUnits += '/' + doseUnitsByBase.time; } value.dose[ iDose ].volume[ mathProperty ] = math.unit( math.multiply( value.dose[ iDose ].mass[ mathProperty ], math.divide( 1, data.preparation.concentration ) ).format() ).to( volumeUnits ); } } } if( value.dose[ iDose ].mass.hasOwnProperty( 'absoluteMax' ) ) { if( value.dose[ iDose ].mass.hasOwnProperty( 'min' ) && math.smaller( value.dose[ iDose ].mass.absoluteMax, value.dose[ iDose ].mass.min ) ) { // Both min and max are larger than the absolute max dose, so just convert to single dose. value.dose[ iDose ].mass.dose = value.dose[ iDose ].mass.absoluteMax; delete value.dose[ iDose ].mass.min; delete value.dose[ iDose ].mass.max; if( value.dose[ iDose ].volume.hasOwnProperty( 'absoluteMax' ) ) { value.dose[ iDose ].volume.dose = value.dose[ iDose ].volume.absoluteMax; delete value.dose[ iDose ].volume.min; delete value.dose[ iDose ].volume.max; } } else if( value.dose[ iDose ].mass.hasOwnProperty( 'max' ) && math.smaller( value.dose[ iDose ].mass.absoluteMax, value.dose[ iDose ].mass.max ) ) { value.dose[ iDose ].mass.max = value.dose[ iDose ].mass.absoluteMax; if( value.dose[ iDose ].volume.hasOwnProperty( 'absoluteMax' ) ) { value.dose[ iDose ].volume.max = value.dose[ iDose ].volume.absoluteMax; } } else if( value.dose[ iDose ].mass.hasOwnProperty( 'dose' ) && math.smaller( value.dose[ iDose ].mass.absoluteMax, value.dose[ iDose ].mass.dose ) ) { value.dose[ iDose ].mass.dose = value.dose[ iDose ].mass.absoluteMax; if( value.dose[ iDose ].volume.hasOwnProperty( 'absoluteMax' ) ) { value.dose[ iDose ].volume.dose = value.dose[ iDose ].volume.absoluteMax; } } } } return value; }; mw.calculators.objectClasses.DrugDosageCalculation.prototype.doRender = function() { var $calculationContainer = $( '.' + this.getContainerClass() ); if( !$calculationContainer.length ) { return; } $calculationContainer.empty(); // Label column var labelAttributes = { class: 'calculator-DrugDosageCalculator-drug-value' }; var labelCss = {}; var $label = $( '<th>', labelAttributes ).css( labelCss ); $label.append( this.getLabelHtml() ); var $infoButton = null; if( this.hasInfo() ) { $infoButton = $( '<a>', { 'data-toggle': 'collapse', href: '#' + this.getContainerClass() + '-info', role: 'button', 'aria-expanded': 'false', 'aria-controls': this.getContainerClass() + '-info' } ) .append( $( '<i>', { class: 'far fa-question-circle' } ) ); $label .append( $( '<span>', { class: 'calculator-calculation-column-label-info' } ) .append( $infoButton ) ); } // Dosage column var $dosage = $( '<td>', { class: 'calculator-DrugDosageCalculator-dose-value' } ); var dash = '-'; // The options column should only show the preparation if there is a calculated volume var hasVolume; if( !this.value || this.value.dosageId === null ) { if( this.value && this.value.hasOwnProperty( 'message' ) ) { $dosage.append( $( '<i>' ).append( this.value.message ) ); } } else { var dosage = this.drug.dosages[ this.value.dosageId ]; var showInfo; var $doseInfo = $( '<div>', { class: 'calculator-DrugDosageCalculator-dose-info' } ); if( dosage.population && dosage.population.id !== DEFAULT_DRUG_POPULATION ) { $doseInfo .append( $( '<div>', { class: 'calculator-DrugDosageCalculator-dose-info-population' } ).append( String( dosage.population ) + ' dosing' ) ); showInfo = true; } if( dosage.hasInfo() ) { var dosageInfoText = mw.calculators.isMobile() ? 'Dosage info' : 'Dosage information'; var $dosageInfoLink = $( '<a>', { 'data-toggle': 'collapse', href: '#' + this.getContainerClass() + '-dose-info-row', role: 'button', 'aria-expanded': 'false', 'aria-controls': this.getContainerClass() + '-dose-info-row' } ) .append( dosageInfoText + ' ' ) .append( $( '<i>', { class: 'far fa-question-circle' } ) ); $doseInfo .append( $( '<div>', { class: 'calculator-DrugDosageCalculator-dose-info-button' } ).append( $dosageInfoLink ) ); showInfo = true; } if( showInfo ) { $dosage.append( $doseInfo ); } // This will iterate through the calculated doses. iDose should exactly correspond to doses within dosage // to allow referencing other properties of the dose. for( var iDose in this.value.dose ) { var dose = dosage.dose[ iDose ]; var doseValue = this.value.dose[ iDose ]; var makeList; if( dose.name ) { $dosage.append( dose.name + '<br />' ); makeList = true; } if( makeList ) { $dosage.append( '<ul>' ); } var administration = dose.getAdministration(); var administrationDisplayed = false; var massPerWeightHtml = ''; if( doseValue.massPerWeight.hasOwnProperty( 'dose' ) ) { massPerWeightHtml += mw.calculators.getValueString( doseValue.massPerWeight.dose ); } else if( doseValue.massPerWeight.hasOwnProperty( 'min' ) && doseValue.massPerWeight.hasOwnProperty( 'max' ) ) { massPerWeightHtml += mw.calculators.getValueNumber( doseValue.massPerWeight.min ); massPerWeightHtml += dash; massPerWeightHtml += mw.calculators.getValueString( doseValue.massPerWeight.max ); } if( massPerWeightHtml ) { if( administration && ! administrationDisplayed ) { massPerWeightHtml += ' ' + administration; administrationDisplayed = true; } var massPerWeightNotesHtml = ''; if( doseValue.mass.hasOwnProperty( 'absoluteMax' ) ) { massPerWeightNotesHtml += 'Max: ' + mw.calculators.getValueString( doseValue.mass.absoluteMax ); } if( dose.weightCalculation && dose.weightCalculation[ 0 ].id !== 'tbw' ) { if( massPerWeightNotesHtml ) { massPerWeightNotesHtml += ', '; } massPerWeightNotesHtml += dose.weightCalculation[ 0 ].getLabelString(); } if( massPerWeightNotesHtml ) { massPerWeightHtml += ' (' + massPerWeightNotesHtml + ')'; } if( makeList ) { massPerWeightHtml = $( '<li>' ).append( massPerWeightHtml ); } $dosage.append( massPerWeightHtml ); if( !makeList ) { $dosage.append( '<br />' ); } } var massHtml = ''; if( doseValue.mass.hasOwnProperty( 'dose' ) ) { massHtml += mw.calculators.getValueString( doseValue.mass.dose ); } else if( doseValue.mass.hasOwnProperty( 'min' ) && doseValue.mass.hasOwnProperty( 'max' ) ) { massHtml += mw.calculators.getValueNumber( doseValue.mass.min ); massHtml += dash; massHtml += mw.calculators.getValueString( doseValue.mass.max ); } if( massHtml ) { if( administration && ! administrationDisplayed ) { massHtml += ' ' + administration; administrationDisplayed = true; } if( dose.weightCalculation.length && doseValue.weightCalculation.id !== dose.weightCalculation[ 0 ].id ) { var weightCalculationLabel = doseValue.weightCalculation.getLabelString(); massHtml += ' (' + weightCalculationLabel + ' ' + $( '<i>', { class: 'far fa-question-circle' } )[ 0 ].outerHTML + ')'; } if( makeList ) { massHtml = $( '<li>' ).append( massHtml ); } $dosage.append( massHtml ); if( !makeList ) { $dosage.append( '<br />' ); } } var volumeHtml = ''; if( doseValue.volume.hasOwnProperty( 'dose' ) ) { volumeHtml += mw.calculators.getValueString( doseValue.volume.dose ); } else if( doseValue.volume.hasOwnProperty( 'min' ) && doseValue.volume.hasOwnProperty( 'max' ) ) { volumeHtml += mw.calculators.getValueNumber( doseValue.volume.min ); volumeHtml += dash; volumeHtml += mw.calculators.getValueString( doseValue.volume.max ); } if( volumeHtml ) { if( administration && ! administrationDisplayed ) { volumeHtml += ' ' + administration; administrationDisplayed = true; } if( makeList ) { volumeHtml = $( '<li>' ).append( volumeHtml ); } $dosage.append( volumeHtml ); if( !makeList ) { $dosage.append( '<br />' ); } hasVolume = true; } if( makeList ) { $dosage.append( '</ul>' ); } } } // Options column var $options = $( '<td>', { class: 'calculator-DrugDosageCalculator-options-value' } ); var indications = this.drug.getIndications(); if( indications.length ) { $options.append( mw.calculators.getVariable( this.getVariableIds().indication ).createInput({ class: 'calculator-container-input-DrugDosageCalculator-options', hideLabelMobile: true, inline: true } ) ); } var routes = this.drug.getRoutes(); if( routes.length ) { $options.append( mw.calculators.getVariable( this.getVariableIds().route ).createInput({ class: 'calculator-container-input-DrugDosageCalculator-options', hideLabelMobile: true, inline: true } ) ); } // Don't show preparations if there isn't a dose with volume if( hasVolume ) { var preparations = this.drug.getPreparations(); if( preparations.length ) { $options.append( mw.calculators.getVariable( this.getVariableIds().preparation ).createInput({ class: 'calculator-container-input-DrugDosageCalculator-options', hideLabelMobile: true, inline: true } ) ); } } $calculationContainer .append( $label, $dosage, $options ); return; var calculation = this; $calculationContainer.each( function() { $( this ).empty(); if( calculation.hasInfo() ) { var infoHtml = ''; if( calculation.description ) { infoHtml += $( '<p>', { html: calculation.description } )[ 0 ].outerHTML; } if( calculation.formula ) { infoHtml += $( '<span>', { class: calculation.getContainerClass() + '-formula' } )[ 0 ].outerHTML; var api = new mw.Api(); api.parse( calculation.formula ).then( function( result ) { $( '.' + calculation.getContainerClass() + '-formula' ).html( result ); } ); } if( calculation.references.length ) { var $references = $( '<ol>' ); for( var iReference in calculation.references ) { $references.append( $( '<li>', { text: calculation.references[ iReference ] } ) ); } infoHtml += $references[ 0 ].outerHTML; } var infoContainerId = calculation.getContainerClass() + '-info'; var $infoContainer = $( '#' + infoContainerId ); if( $infoContainer.length ) { $infoContainer.empty(); } $infoContainer = $( '<tr>', { id: infoContainerId, class: 'collapse' } ) .append( $( '<td>', { colspan: 2 } ).append( infoHtml ) ); $( this ).after( $infoContainer ); } } ); }; mw.calculators.objectClasses.DrugDosageCalculation.prototype.getCalculationData = function() { var inputData = new mw.calculators.objectClasses.CalculationData(); // Add variables created by this calculation var variableIds = this.getVariableIds(); for( var variableType in variableIds ) { inputData.variables.optional.push( variableIds[ variableType ] ); } var dataTypes = inputData.getDataTypes(); // Data is only actually required if it is required by every dosage for the drug. // Data marked as required by an individual dosage that does not appear in every // dosage will be converted to optional. var requiredInputData = new mw.calculators.objectClasses.CalculationData(); // Need a way to tell the first iteration of the loop to initialize the required variables to a value that // is distinct from the empty array (populated across loop using array intersect, so could become [] and shouldn't // reinitialize). var initializeRequiredData = true; // Iterate through each dosage to determine variable dependency for( var iDosage in this.drug.dosages ) { var dosageInputData = this.drug.dosages[ iDosage ].getCalculationData(); inputData = inputData.merge( dosageInputData ); for( var iDataType in dataTypes ) { var dataType = dataTypes[ iDataType ]; if( initializeRequiredData ) { requiredInputData[ dataType ].required = inputData[ dataType ].required; } else { // Data is only truly required if it is required by all dosage calculations, so use array intersection requiredInputData[ dataType ].required = requiredInputData[ dataType ].required.filter( function( index ) { return dosageInputData[ dataType ].required.indexOf( index ) !== -1; } ); } } initializeRequiredData = false; } for( var iDataType in dataTypes ) { var dataType = dataTypes[ iDataType ]; // Move any data marked required in inputData to optional if it not actually required (i.e. doesn't appear // in requiredInputData). inputData[ dataType ].optional = inputData[ dataType ].optional.concat( inputData[ dataType ].required.filter( function( index ) { return requiredInputData[ dataType ].required.indexOf( index ) === -1; } ) ).filter( mw.calculators.uniqueValues ); inputData[ dataType ].required = requiredInputData[ dataType ].required; } return inputData; }; mw.calculators.objectClasses.DrugDosageCalculation.prototype.getCalculationDataValues = function() { var data = mw.calculators.objectClasses.AbstractCalculation.prototype.getCalculationDataValues.call( this ); data.drug = this.drug; data.indication = data[ this.getVariablePrefix() + 'indication' ] !== null ? mw.calculators.getDrugIndication( mw.calculators.getVariable( this.getVariableIds().indication ).getValue() ) : null; delete data[ this.getVariablePrefix() + 'indication' ]; data.preparation = data[ this.getVariablePrefix() + 'preparation' ] !== null ? this.drug.preparations[ mw.calculators.getVariable( this.getVariableIds().preparation ).getValue() ] : null; delete data[ this.getVariablePrefix() + 'preparation' ]; data.route = data[ this.getVariablePrefix() + 'route' ] !== null ? mw.calculators.getDrugRoute( mw.calculators.getVariable( this.getVariableIds().route ).getValue() ) : null; delete data[ this.getVariablePrefix() + 'route' ]; return data; }; mw.calculators.objectClasses.DrugDosageCalculation.prototype.getLabelHtml = function() { var $label = $( '<a>', { href: mw.util.getUrl( this.drug.name ), text: this.drug.name } ).css( 'background-color', '#fff' ); var highlightColor = this.drug.color.getHighlightColor(); if( highlightColor ) { var highlightContainerAttributes = { class: 'calculator-DrugDosageCalculator-drug-highlight' }; var highlightContainerCss = {}; highlightContainerCss[ 'background' ] = highlightColor; $label = $( '<span>', highlightContainerAttributes ).append( $label ).css( highlightContainerCss ); } var primaryColor = this.drug.color.getPrimaryColor(); if( primaryColor ) { var backgroundContainerAttributes = { class: 'calculator-DrugDosageCalculator-drug-background' }; var backgroundContainerCss = {}; if( this.drug.color.isStriped() ) { backgroundContainerCss[ 'background' ] = 'repeating-linear-gradient(135deg,rgba(0,0,0,0),rgba(0,0,0,0)10px,rgba(255,255,255,1)10px,rgba(255,255,255,1)20px),' + primaryColor; } else { backgroundContainerCss[ 'background'] = primaryColor; } $label = $( '<span>', backgroundContainerAttributes ).append( $label ).css( backgroundContainerCss ); } return $label; }; mw.calculators.objectClasses.DrugDosageCalculation.prototype.getProperties = function() { var inheritedProperties = mw.calculators.objectClasses.AbstractCalculation.prototype.getProperties(); return this.mergeProperties( inheritedProperties, { required: [ 'drug' ], optional: [] } ); }; mw.calculators.objectClasses.DrugDosageCalculation.prototype.getVariableIds = function() { return { indication: this.getVariablePrefix() + 'indication', preparation: this.getVariablePrefix() + 'preparation', route: this.getVariablePrefix() + 'route' }; }; mw.calculators.objectClasses.DrugDosageCalculation.prototype.getVariableOptions = function( variableId ) { if( variableId === this.getVariablePrefix() + 'indication' ) { return this.drug.getIndications(); } else if( variableId === this.getVariablePrefix() + 'preparation' ) { return this.drug.getPreparations(); } else if( variableId === this.getVariablePrefix() + 'route' ) { return this.drug.getRoutes(); } }; mw.calculators.objectClasses.DrugDosageCalculation.prototype.getVariablePrefix = function() { return this.drug.id + '-'; }; mw.calculators.objectClasses.DrugDosageCalculation.prototype.initialize = function() { if( typeof this.drug === 'string' ) { var drug = mw.calculators.getDrug( this.drug ); if( !drug ) { throw new Error( 'DrugDosage references drug "' + this.drug + '" which is not defined' ); } this.drug = drug; } this.updateVariables(); mw.calculators.objectClasses.AbstractCalculation.prototype.initialize.call( this ); }; mw.calculators.objectClasses.DrugDosageCalculation.prototype.updateVariables = function() { var variableIds = this.getVariableIds(); for( var variableType in variableIds ) { var variableId = variableIds[ variableType ]; var variableOptions = this.getVariableOptions( variableId ); var variableOptionValues = {}; var defaultOption = 0; for( var iVariableOption in variableOptions ) { var variableOption = variableOptions[ iVariableOption ]; defaultOption = variableOption.default ? iVariableOption : defaultOption; variableOptionValues[ variableOption.id ] = String( variableOption ); } var defaultValue = variableOptions.length ? variableOptions[ defaultOption ].id : null; var variable = mw.calculators.getVariable( variableId ); if( !variable ) { var newVariable = {}; newVariable[ variableId ] = { name: variableType.charAt(0).toUpperCase() + variableType.slice(1), type: 'string', defaultValue: defaultValue, options: variableOptionValues }; mw.calculators.addVariables( newVariable ); } else { // Probably not ideal to reach into the variable to change these things directly // Perhaps add helper functions to variable class mw.calculators.variables[ variableId ].defaultValue = defaultValue; mw.calculators.variables[ variableId ].options = variableOptionValues; } } }; mw.calculators.addDrugCalculators = function( moduleId, drugCalculatorData, className ) { className = className ? className : 'DrugDosageCalculator'; for( var drugCalculatorId in drugCalculatorData ) { drugCalculatorData[ drugCalculatorId ].module = moduleId; for( var iCalculation in drugCalculatorData[ drugCalculatorId].calculations ) { drugCalculatorData[ drugCalculatorId].calculations[ iCalculation ] = moduleId + '-' + drugCalculatorData[ drugCalculatorId].calculations[ iCalculation ]; } } mw.calculators.addCalculators( moduleId, drugCalculatorData, className ); }; /** * Class DrugDosageCalculator * @param {Object} propertyValues * @returns {mw.calculators.objectClasses.DrugDosageCalculator} * @constructor */ mw.calculators.objectClasses.DrugDosageCalculator = function( propertyValues ) { mw.calculators.objectClasses.CalculatorObject.call( this, this.getProperties(), propertyValues ); }; mw.calculators.objectClasses.DrugDosageCalculator.prototype = Object.create( mw.calculators.objectClasses.AbstractCalculator.prototype ); mw.calculators.objectClasses.DrugDosageCalculator.prototype.doRender = function() { var $calculatorContainer = $( '.' + this.getContainerClass() ); if( !$calculatorContainer.length ) { return; } $calculatorContainer.addClass( this.getCalculatorClass() ); $calculatorContainer.empty(); $calculatorContainer.append( $( '<h4>', { text: this.name } ) ); var $calculationsContainer = $( '<table>', { class: 'wikitable' } ).append( '<tbody>' ); $calculatorContainer.append( $calculationsContainer ); $calculationsContainer .append( $( '<tr>' ) .append( $( '<th>', { class: this.getCalculatorClass() + '-drug' } ).text( 'Drug' ), $( '<th>', { class: this.getCalculatorClass() + '-dose' } ).text( 'Dose' ), $( '<th>', { class: this.getCalculatorClass() + '-options' } ).text( 'Options' ) ) ); for( var iCalculationId in this.calculations ) { var calculation = mw.calculators.getCalculation( this.calculations[ iCalculationId ] ); var calculationContainerClass = calculation.getContainerClass(); var $calculationContainer = $( '<tr>', { class: calculationContainerClass } ); $calculationsContainer.append( $calculationContainer ); calculation.render(); } }; mw.calculators.objectClasses.DrugDosageCalculator.prototype.getCalculatorClass = function() { return 'calculator-DrugDosageCalculator'; }; mw.calculators.objectClasses.DrugDosageCalculator.prototype.getProperties = function() { var inheritedProperties = mw.calculators.objectClasses.AbstractCalculator.prototype.getProperties(); return this.mergeProperties( inheritedProperties, { required: [], optional: [] } ); }; }() );